Thiochrome

Thiochrome

$100.00 - 0.25 mg

$350.00 - 1 mg

All prices in Australian dollars

Code
BIA-T2477
Synonyms
NSC 56339
CAS #
92-35-3
Molecular Formula
C12H14N4OS
Molecular Weight
262.33
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

Download Data Sheets

Product Data Sheet

Application Notes

Thiochrome is a fluorescent yellow tricyclic alcohol found in yeast formed by oxidation of thiamine. Thiochrome is used analytically to determine thiamine levels. Thiochrome binds allosterically to muscarinic receptors and selectively enhances the affinity of M4 muscarinic receptor for acetylcholine 3- to 5-fold. Thiochrome has antioxidant properties.

References

  • Flow-injection solvent extraction without phase separation: Fluorimetric determination of thiamine by the thiochrome method. Alonso A. et al. J Pharm Biomed Anal. 2006, 42, 171.
  • Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity. Lazareno S. et al. Molec Pharmacol. 2004, 65, 257.
  • Antioxidant properties of thiamine and its hydrophobic metabolites. Stsiapura, V. I.; Stepuro I.I. Handbook of free radicals: formation, types and effects 2010, 319. Ed. Kozyrev D. and Slutsky V.

Other Products

Related products