$166.00 - 0.25 mg
$581.00 - 1 mg
All prices in Australian dollars
- MBI 005, Thaxtomine A
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in DMSO or dimethyl formamide; partially soluble in methanol or 100% ethanol; poorly soluble in water
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Thaxtomin A is a unique dioxopiperazine containing a 4-nitroindol-3-yl moiety isolated by scientists at Dow Agrisciences from Streptomyces scabies, the causative agent of common scab on new potatoes in 1989. Thaxtomin A is the predominant and most active member of the thaxtomin group of phytotoxins. Thaxtomin A acts as a herbicide via inhibition of cellulose biosynthesis. Atypical programmed cell death induced by thaxtomin A can be ameliorated by hydrogen peroxide. Thaxtomin A dysregulates K+ and Ca2+ fluxes in the roots of Arabidopsis.
- Isolation and characterization of phytotoxins associated with Streptomyces scabies. King R.R. et al. J Chem Soc Chem Commun. 1989, 849.
- Herbicidal properties of the thaxtomin group of phytotoxins. King R.R. & Lawrence C.H. J Agric Food Chem. 2001, 49, 2298.
- Reactive oxygen species alleviate cell death induced by thaxtomin A in Arabidopsis thaliana cell cultures. Awwad F. et al. Plants 2019, 8.