Sultriecin

Sultriecin

$287.00 - 0.50 mg

$1,005.00 - 2.50 mg

All prices in Australian dollars

Synonyms
BU 3285T
CAS #
131774-59-9
Molecular Formula
C23H34O8PNa
Molecular Weight
492.5
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in water, optimial stability in aqueous buffered solutions at pH 6.5. NOTE: hydrolysis of the phosphate ester will result from inappropriate storage.
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Application Notes

Sultriecin is the dominant analogue in a family of triene antibiotics originally thought to be sulfate esters, but recently unequivocally proven to be phosphate esters. While re-naming of the compound as ‘phostriecin’ may cause confusion with ‘fostriecin’, it is now recognised that sultriecin is a phosphate ester of fostriecin. Sultriecin displays potent antifungal and antitumor activity.

References

  • Sultriecin, a new antifungal and antitumor antibiotic from Streptomyces roseiscleroticus. Production, isolation, structure and biological activity. Ohkuma, H. et al., J. Antibiot. 1992, 45, 1239.
  • Fostriecin: chemistry and biology. Lewy D.S. Curr. Med. Chem. 2002, 9, 2005.

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