$66.00 - 5 mg
$231.00 - 25 mg
All prices in Australian dollars
- Penicillanic acid 1,1-dioxide sodium
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO.
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Sulbactam sodium is a semi-synthetic penem antibiotic formed by the oxidation of penicillanic acid to its sulfone and was invented by Barth at Pfizer in 1978. Sulbactam sodium is a weak antibiotic but its action as an irreversible inhibitor of β-lactamase is exploited to block the degradation of other penicillin derivatives. Sulbactam acts as a synergist with cephalosporins and penicillins against Gram positive bacteria and is used commercially in combination with ampicillin.
- Penicillanic acid 1,1-dioxides as beta-lactamase inhibitors. Barth W.E. US Patent 41,234,579 1980.
- CP-45,899 in combination with penicillin or ampicillin against penicillin-resistant Staphylococcus, Haemophilus influenzae, and Bacteroides. Retsema J.A. et al., Antimicrob. Agents Chemother. 1980, 17, 615.
- Sulbactam/Ampicillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Campoli-Richards D.M. and Brogden R.N. Drugs 1987, 33, 577.