Sch 38519
Application Notes
Sch 38519 is an isochromanequinone, structurally related to lactoquinomycin. Sch 38519 inhibits thrombin-induced aggregation of human platelets and is active against Gram positive and Gram negative bacteria.
References
- A new isochromanequinone antibiotic, SCH 38519, with a novel sugar linkage. Hegde V R. et al., Tet. Lett. 1987, 28, 4485.
- Sch 38519, a novel platelet aggregation inhibitor produced by a Thermomonospora sp. Taxonomy, fermentation, isolation, physico-chemical properties, structure and biological properties. Patel M. et al., J. Antibiot. 1989, 42, 1063.