Reveromycin B
Reveromycin B
$325.00 - 0.25 mg
$1,140.00 - 1 mg
All prices in Australian dollars
- Code
- BIA-R1079
- CAS #
- 144860-68-4
- Molecular Formula
- C36H52O11
- Molecular Weight
- 660.8
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Download Data Sheets
Application Notes
Reveromycin B is an analogue of reveromycin A formed by rearrangement of the 6:6 spiroketal to a 5:6 spiroketal. Lacking much of the biological activity of reveromycin A, reveromycin B is a useful negative control in resolving the mode of action of this class.
References
- Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities. Takahashi H. et al., J. Antibiot. 1992, 45, 1414.
- Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A. Miyamoto Y., et al., J. Biol. Chem., 2002, 277, 28810.
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