Resistomycin

Resistomycin

$160.00 - 1 mg

$560.00 - 5 mg

All prices in Australian dollars

Code
BIA-R1076
Synonyms
Croceomycin, Geliomycin, Heliomycin, Itamycin, 11-98, A 3733A, X 340
CAS #
20004-62-0
Molecular Formula
C22H16O6
Molecular Weight
376.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.

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Application Notes

Resistomycin is a tetrahydroxyanthrone that has been independently isolated by several groups and reported to have a broad range of biological activities. Resistomycin is active against bacteria, including mycobacteria, and viruses. Resistomycin induces apoptosis and inhibits RNA polymerase.

References

  • Effects of polyphenolic anthrone derivatives, resistomycin and hypercin, on apoptosis in human megakaryoblastic leukemia CMK-7 cell line. Shiono Y. et al., Z Naturforsch. [C] 2002, 57, 923.
  • 3-Alkanoyl-5-hydroxymethyl tetronic acid homologues and resistomycin: new inhibitors of HIV-1 protease. I. Fermentation, isolation and biological activity. Roggo B.E. J. Antibiot. 1994, 47, 136.
  • Molecular structure of heliomycin, an inhibitor of RNA synthesis. Arora S.K. J. Antibiot. 1985, 38, 113

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