Pyrenophorol

Pyrenophorol

$280.00 - 0.50 mg

$980.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-P1407
Synonyms
(-)-Pyrenophorol, Helmidiol
CAS #
22248-41-5
Molecular Formula
C16H24O6
Molecular Weight
312.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

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Application Notes

Pyrenophorol is a simple macrocyclic dilactone produced by a number of species of pathogenic fungi, including Byssochlamys, Stenphyllum, Alternaria and Drechslera, first reported in the late 1960s. Pyrenophorol exhibits antibiotic, herbicidal and anthelmintic properties, and is a weak inhibitor of propyl endopeptidases. Pyrenophorol inhibits seed germination but once the seed is germinated, pyrenophlorol enhances root development but causes abnormal chlorophyll retention in leaf sections.

References

  • Isolation of pyrenophorol. Kis Z. et al., Experientia 1969, 25, 123.
  • Albocycline and carbomycin-type macrolides, inhibitors of human propyl endopeptideases. Christner C. et al., J. Antibiot 1998, 51, 368.
  • Bioactivity of the fungal metabolite (8R,16R)-(-)-pyrenophorin on graminaceous plants. Kastanias M.A. & Chrysayi-Tokousbalides M. J. Agric. Food Chem. 2005, 53, 5943.

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