Pseudomonic acid

Pseudomonic acid

$195.00 - 25 mg

$55.00 - 5 mg

All prices in Australian dollars

Code
BIA-P1206
Synonyms
Mupirocin, Bactroban, Eismycin, BRL 4910A, Y 11633
CAS #
12650-69-0
Molecular Formula
C26H44O9
Molecular Weight
500.6
Purity
>95% by HPLC
Long Term Storage
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

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Product Data Sheet

Application Notes

Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens, reported by Fuller et al., in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.

References

  • Pseudomonic acid: an antibiotic produced by Pseudomonas fluorescens. Fuller A.T. et al., Nature 1971, 234, 416.
  • Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Sutherland R., Antimicrob Agents Chemother. 1985, 27, 495.
  • Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid. Hughes J. & Mellows G., Biochem. J. 1978, 176, 305.

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