Pseudomonic acid
Pseudomonic acid
$195.00 - 25 mg
$55.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-P1206
- Synonyms
- Mupirocin, Bactroban, Eismycin, BRL 4910A, Y 11633
- CAS #
- 12650-69-0
- Molecular Formula
- C26H44O9
- Molecular Weight
- 500.6
- Purity
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes
Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens, reported by Fuller et al., in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.
References
- Pseudomonic acid: an antibiotic produced by Pseudomonas fluorescens. Fuller A.T. et al., Nature 1971, 234, 416.
- Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Sutherland R., Antimicrob Agents Chemother. 1985, 27, 495.
- Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid. Hughes J. & Mellows G., Biochem. J. 1978, 176, 305.