Pneumocandin B0
Pneumocandin B0
$250.00 - 1 mg
$875.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-P1274
- CAS #
- 135575-42-7
- Molecular Formula
- C50H80N8O17
- Molecular Weight
- 1065.2
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Download Data Sheets
Application Notes
Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from some species of Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
References
- 671,329, a new antifungal agent I. Fermentation and isolation. Schwartz R. E. et al., J Antibiot. 1989, 42, 163.
- 671,329, a new antifungal agent II. Structure determination Wichmann C. F. et al., J Antibiot. 1989, 42, 168.
- L-671,329, a new antifungal agent. III. In vitro activity, toxicity and efficacy in comparison to aculeacin. Fromtling R. A. & Abruzzo G. K. J. Antibiot. 1989, 42, 168.
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