Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from some species of Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
- 671,329, a new antifungal agent I. Fermentation and isolation. Schwartz R. E. et al., J Antibiot. 1989, 42, 163.
- 671,329, a new antifungal agent II. Structure determination Wichmann C. F. et al., J Antibiot. 1989, 42, 168.
- L-671,329, a new antifungal agent. III. In vitro activity, toxicity and efficacy in comparison to aculeacin. Fromtling R. A. & Abruzzo G. K. J. Antibiot. 1989, 42, 168.