Pneumocandin B0

Pneumocandin B0

$250.00 - 1 mg

$875.00 - 5 mg

All prices in Australian dollars

Code
BIA-P1274
CAS #
135575-42-7
Molecular Formula
C50H80N8O17
Molecular Weight
1065.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from some species of Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.

References

  • 671,329, a new antifungal agent I. Fermentation and isolation. Schwartz R. E. et al., J Antibiot. 1989, 42, 163.
  • 671,329, a new antifungal agent II. Structure determination Wichmann C. F. et al., J Antibiot. 1989, 42, 168.
  • L-671,329, a new antifungal agent. III. In vitro activity, toxicity and efficacy in comparison to aculeacin. Fromtling R. A. & Abruzzo G. K. J. Antibiot. 1989, 42, 168.

Other Products

Related products