$371.00 - 1 mg
$1,299.00 - 5 mg
All prices in Australian dollars
- VM 29919
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Paraherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins. Subsequent research identified a potent, non-toxic paralysis of nematodes which led to the metabolite's development as a candidate anthelmintic. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors.
- The structure of parherquamide, a toxic metabolite from Penicillium paraherquei. Yamazaki M.E. et al., Tetrahedron Lett. 1982, 22, 135.
- Novel antinematocidal and antiparasitic agents from Penicillium charlesii I. Fermentation, isolation and biological activity. Ondeyka J.G. J. Antibiot. 1990, 43, 1375.
- Paraherquamide and 2-deoxy-paraherquamide distinguish cholinergic receptor subtypes in Ascaris muscle. Robertson A.P. et al., J. Pharmacol. Exp. Ther. 2002, 302, 853.