Oxychloroaphine

Oxychloroaphine

$110.00 - 1 mg

$385.00 - 5 mg

All prices in Australian dollars

Code
BIA-O1527
Synonyms
Oxychloraphin, Phenazine-1-carboxyamide, Xanthoraphine
CAS #
550-89-0
Molecular Formula
C13H9N3O
Molecular Weight
223.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Oxychloroaphine (1-phenazinecarboxamide) is a simple phenazine produced by several species of Pseudomonas. Oxychloroaphine is a weakly active antifungal metabolite that plays a role in the biocontrol of plant diseases by several Pseudomonas strains. Oxychloroaphine and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives.

References

  • Antibiotic substances produced by Pseudomonas aeruginosa. Hays E.E et al., J. Biol. Chem. 1945, 159, 725.
  • Biosynthesis and regulation of phenazine compounds in Pseudomonas spp. Mavrodi D.V. et al., in Pseudomonas, model organism, pathogen, cell factory. (B.H.A. Verlag GmbH & Co. Germany) 2009, 331.

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