Oxindole is a simple indole analogue isolated from both bacteria (Chromobacterium violaceum) and fungi (a basidiomycete, Calyptella sp. and an ascomycete, Pencillium sp.). Oxindole exists as the dominant tautomer of 2-hydroxyindole both in solution and as a solid. Oxindole has been reported as an inhibitor of phospholipase A2 and platelet aggregation. Its unusual distribution in microbes makes oxindole a useful standard for analytical and bioassay dereplication of crude microbial extracts.
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