Ornithine lactam , D-

Ornithine lactam , D-

$65.00 - 1 mg

$230.00 - 5 mg

All prices in Australian dollars

Code
BIA-O2217
Synonyms
(3R)-3-Amino-2-piperidinone
CAS #
88763-76-2
Molecular Formula
C5H10N2O
Molecular Weight
114.15
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Application Notes

D-Ornithine lactam is the “unnatural” isomer the endogenous metabolite, L-ornithine lactam which when found in excess in plasma is a measure of a rare autosomal recessive disorder of the urea cycle. A possible role for D-ornithine lactam as a bioactive co-metabolite has received little attention. To date D-ornithine lactam application is as a control to aid in the exploration of the biological role of L-ornithine lactam.

References

  • The hyperornithinemia–hyperammonemia-homocitrullinuria syndrome. Martinelli D. et al. J Rare Dis. 2015, 10, 29.
  • Cosmetic and topical preparations containing ornithine lactam. Suetsugu M. and Yoshida Y. Jpn. Kokai Tokkyo Koho 2000, JP 2000086481 A 20000328.
  • Identification of ornithine-​lactam converted from arginine in Streptomyces incarnatus NRRL8089. Fukuda K. et al. Okayama Daigaku Nogakubu Gakujutsu Hokoku 2010, 99, 1. 

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