$302.00 - 1 mg
$1,057.00 - 5 mg
All prices in Australian dollars
- 12-Deoxyoligomycin A
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Oligomycin C, a minor component of the oligomycin complex isolated from selected strains of Streptomyces, is an inhibitor of mitochondrial F1F0-ATPase. It makes cells more susceptible to cell death, and also leads to a switch in the death mode from apoptosis to necrosis.
- Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis. Miyoshi N. et al., Proc. Natl Acad. Sci. USA 2006, 103, 1727.
- Mitochondria in eosinophils: functional role in apoptosis but not respiration. Peachman K.K. et al., Proc. Natl Acad. Sci. USA 2001, 98, 1717.
- The BH3 domain is required for caspase-independent cell death induced by Bax and oligomycin. Fitch M.E. et al., Cell Death Differ. 2000, 7, 338.