Nanangenine C

Nanangenine C

$200.00 - 1 mg

$700.00 - 5 mg

All prices in Australian dollars

CAS #
NA
Molecular Formula
C21H32O5
Molecular Weight
364.5
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

The nanangenines are newly discovered drimane sesquiterpenoid metabolites from a hitherto undescribed Australian fungus, Aspergillus nanangensis. Nanangenine D is a drimane lactone bearing a C6/8 acyl side chain. Nanangenine D has potent activity against B. subtilis (IC50 5.7 μg/mL) and NS-1 cell line (IC50 4.1 μg/mL). but was inactive against tumor cell lines (mouse myeloma NS-1 cell, human prostate DU-145 and human breast adenocarcinoma MC-7) and neonatal foreskin. The nanangenines did not exhibit Gram negative or antifungal activity.

References

  • Nanangenines: drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis. Lacey H.J. et al. Beilstein J Org Chem 2019, 15, 2631.

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