Milbemycin A3

Milbemycin A3

$360.00 - 1 mg

$1,260.00 - 5 mg

All prices in Australian dollars

Code
BIA-M1051
Synonyms
B 41A3, Milbemycin alpha1, Milbemectin, Milbemectin A3
CAS #
51596-10-2
Molecular Formula
C31H44O7
Molecular Weight
528.7
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A3 is a major member of a group of analogues containing a 25-methyl substituent. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act by opening glutamate sensitive chloride channels.

References

  • Milbemycins, a new family of macrolide antibiotics: fermentation, isolation and physico-chemical properties.Takiguchi Y. et al., J Antibiot. 1980, 33, 1120.
  • Milbemycins, a new family of macrolide antibiotics: producing organism and its mutants. Okazaki T. et al., J Antibiot. 1983, 36, 438.

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