Micafungin sodium

Micafungin sodium

$280.00 - 1 mg

$980.00 - 5 mg

All prices in Australian dollars

Code
BIA-M1550
Synonyms
Mycamine
CAS #
208538-73-2
Molecular Formula
C56H70N9NaO23S
Molecular Weight
1292.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Moderater water solubility.

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Application Notes

Micafungin sodium is the salt of the semi-synthetic cyclic lipopeptide, micafungin, a member of the echinocandin class that was reported in 1999 from Fujisawa in Japan. The sodium salt takes advantage of the aryl sulfate moiety providing improved water solubility and is the preferred salt for pharmaceutical applications. Like all echinocandins, micafungin inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.

References

  • FK463, a novel water-soluble echinocandin lipopeptide: Synthesis and antifungal activity. Tomishima M. et al., J. Antibiot. 1999, 52, 674.

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