Methoxycanthinone, 5-

Methoxycanthinone, 5-

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-M1940
Synonyms
5-Methoxycanthin-6-one, NSC 88929
CAS #
15071-56-4
Molecular Formula
C15H10N2O2
Molecular Weight
250.25
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

Download Data Sheets

Product Data Sheet

Application Notes

5-Methoxycanthinone is a β-carboline first isolated from the Australian Rutaceae Pentaceras Australis Hook by Price and co-workers at the CSIRO, Australia in 1952. 5-Methoxycanthinone is a modest inhibitor of a panel of the human tumor cell lines: epiderimoid carcinoma of the nasopharynx (KB), lung carcinoma (A-549), ileocecal carcinoma (HCT-8), renal cancer (CAKI-1), breast cancer (MCF-7), melanoma (SK-MEL-2) with ED50 of 2.9, 3.1, 2.5, 4.4, 5.0 and 17 µg/mL​.

References

  • Alkaloids of the Australian Rutaceae: Pentaceras Australis Hook. F. II. Identification of 5-​methoxycanthinone. Haynes H.G. et al. Aust J Sci, Res Ser B. 1952, A5, 563.
  • Anti-​HIV agents 45 and antitumor agents 205. Two new sesquiterpenes, leitneridanins A and B, and the cytotoxic and anti-​HIV principles from Leitneria floridana. Xu Z. et al. J Nat Prod. 2000, 63, 1712.

Other Products

Related products