Mer-NF5003E

Mer-NF5003E

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-M1846
Synonyms
NF 5003E, L 671776
CAS #
159121-98-9
Molecular Formula
C23H32O5
Molecular Weight
388.5
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Mer-NF5003E is a sesquiterpenoid mycotoxin isolated from Stachybotrys strains, first published in 1994 as an avian myeloblastosis virus (AMV) protease inhibitor. Mer-NF5003E is inactive against HIV due to host cell toxicity. An analogue, Mer-NF5003B has been isolated from fungal biomass and dust samples collected in a domestic facility and may be a useful biomarker to assess exposure to potentially harmful S. chartarum contamination.

References

  • Mer-NF5003B, E and F, novel sesquiterpenoids as avian myeloblastosis virus protease inhibitors produced by Stachybotrys sp.. Kaneta R. et al., J. Antibiot. 1994, 47,727.
  • Stachybotrys mycotoxins: from culture extracts to dust samples. Dosen I. et al., Anal. Bioanal. Chem. 2016, 408, 5513.

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