Lasalocid sodium

Lasalocid sodium

$140.00 - 5 mg

$490.00 - 25 mg

All prices in Australian dollars

Code
BIA-L1302
Synonyms
Avatec, Bovatec, Ro 2-2985, X 537A
CAS #
25999-20-6
Molecular Formula
C34H53NaO8
Molecular Weight
612.8
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Lasalocid sodium is a salt of the polyether ionophore lasalocid, with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia. Lasalocid is able to form neutral complexes with monovalent and divalent cations and transport the ions through apolar phase, including lipid bilayer membranes. Interestingly, lasalocid can also transport larger organic cations, e.g. protonated dopamine.

References

  • The Isolation of three new crystalline antibiotics from Streptomyces. Berger J. et al., J. Am. Chem. Soc. 1951, 73, 5295.
  • Structure of antibiotic X-537A. Westley J. W. J. Chem. Soc. D, 1970, 71.
  • Biosynthesis of antibiotic X-537A. Westley, J.W. et al., J. Chem. Soc. D, 1970, 1467.
  • The effect of amine structure on complexation with lasalocid in model membrane systems. I. Identification of charged complexes in lipid bilayer membranes. Kinsel J.F. Biochim Biophys Acta. 1982, 684, 233.

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