Kinetin riboside

Kinetin riboside

Kinetin riboside

$70.00 - 5 mg

$245.00 - 25 mg

All prices in Australian dollars

Code
BIA-K3070
Synonyms
Furfuryladenosine, NSC 120958, Ribosylkinetin
CAS #
4338-47-0
Molecular Formula
C15H17N5O5
Molecular Weight
347.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol and DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Kinetin riboside is a natural product detected in coconut water (Cocos nucifera) which exhibits stimulatory effects on plant growth and cell division. Kinetin riboside has potent antitumor activity against human leukemia, melanoma and pancreas cell lines, and is pro-apoptotic leading to increases in levels of Bax and decreased levels of Bcl-2. Kinetin riboside augments the antibacterial effect of chlortetracycline against S. albus and S. aureus. Kinetin riboside activates the Parkinson’s disease target PINK1 kinase.

References

  • King D.E. et al. (2006). New classification and update on the quinolone antibiotics. Am. Fam. Physician 61, 3741.
  • Dudzik P. (2011). Effects of kinetin riboside on proliferation and proapoptotic activities in human normal and cancer cell lines. J. Cell. Biochem., 112, 2115.
  • Osgerby L. (2017). Kinetin riboside and its protides activate the Parkinson’s disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization. J. Med. Chem., 60, 3518.

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