Khellin is a constituent of the fruit of Ammi visnaga structurally related to psoralen. Khellin displays a range of pharmacological activities including anthelmintic, bronchodilator, vasodilator and antidiabetic properties. Khellin exhibits spasmolytic activity. Khellin is a photosensitising agent which has been used for the treatment of vitiligo in humans. Khellin may intercalate with DNA.
- S 6. Furochromones. Part I. The synthesis of khellin. Baxter R.A. et al. J Chem Soc. 1949, S30-S33.
- Pharmacological actions of the crystalline principles of Ammi visnaga. Anrep G.V. et al. J Pharmacy Pharmacol. 1949, 1, 164.
- Phototherapeutic, photobiologic, and photosensitizing properties of khellin. Morliere D. et al. J Inv Dermatol. 1988, 90, 720.