JBIR-15 is a non-proteogenic cyclic tripeptide isolated from a marine sponge-derived Aspergillus sclerotiorum by researchers at BIRC, Japan in 2009. JBIR-15 is N-demethylaspochracin, the macrocycle comprising alanine, N-methylvaline and an ornithine cyclised through the delta rather than the alpha-amino group. The alpha amino is acylated with an octa-2,4,6-trienoic acid. JBIR-15 is known to be non-toxic to mammalian cell lines and insects but its biological activity is largely unexplored.