Ivermectin B1a, epi-

Ivermectin B1a, epi-

$315.00 - 1 mg

$1,105.00 - 5 mg

All prices in Australian dollars

Code
BIA-I1578
CAS #
??
Molecular Formula
C48H74O14
Molecular Weight
875.1
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

epi-Ivermectin B1a is a base-catalysed intermediate in the decomposition of ivermectin. epi-Ivermectin B1a is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue, Δ2-ivermectin B1a. Despite the importance of ivermectin as an anthelmintic in animal health, there are no published reports of the biological activity or the levels of epi-ivermectin B1a in animals or the environment.

References

  • Base-catalyzed isomerization of avermectins. Pivnichny J.V. et al., J. Agric. Food Chem. 1988, 36, 826.
  • Direct determination of avermectins in plasma at nanogram levels by High-Performance Liquid Chromatography. Pivnichny J.V. et al., J. Pharm. Sci. 1980, 72, 1447.

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