Indole-3-carboxylic acid

Indole-3-carboxylic acid

$67.00 - 25 mg

$235.00 - 100 mg

All prices in Australian dollars

Code
BIA-I2373
Synonyms
1H-​Indole-​3-​carboxylic acid, 3-Carboxyindole, Indol-3-carboxylic acid, Indole-β-carboxylic acid, β-Indolylcarboxylic acid
CAS #
771-50-6
Molecular Formula
C9H7NO2
Molecular Weight
161.16
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Application Notes

Indole-3-carboxylic acid is a tryptophan metabolite produced by microbiota in the human gut. Indole-3-carboxylic acid isolated from Streptomyces sp. is active against Gram positive bacteria, yeast and fungi. Indole-3-carboxylic acid induces resistance in Arabidopsis adult plants against the necrotrophic fungus Plectosphaerella cucumerina through primed callose accumulation. Indole-3-carboxylic acid is a useful skeleton for the design and synthesis of bioactive molecules.

References

  • Purification and biological evaluation of the metabolites produced by Streptomyces sp. TK-​VL_333. Kavitha A. et al. Res Microbiol. 2010, 161, 335.
  • Accumulating evidences of callose priming by indole- 3- carboxylic acid in response to Plectospharella cucumerina. Pastor-Fernandez J. et al. Plant Signal Behav. 2019, 14, 1608107.
  • Design, synthesis and preliminary biological evaluation of indole-​3-​carboxylic acid-​based skeleton of Bcl-​2​/Mcl-​1 dual inhibitors. Liu T. et al. Bioorg Med Chem. 2017, 25, 1939.

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