Illudin B
Application Notes
Illudin B is a novel sesquiterpene isolated from Clitocybe illudens (Omphalotus olearius) by Italian researchers in 1991. The biological activity of illudin B has not been published, however its analogues, Illudin S and illudin M are potent antitumor actives, binding to DNA.
References
- Secondary mould metabolites. Part 31. Isolation and structure elucidation of illudins A and B, and illudalenol, new sesquiterpenoids from Clitocybe illudens. Arnone A. et al. J Chem Soc Perkin Trans 1., 1991, 733.
- The structure of the basidiomycete metabolites, illudin S and illudin M. McMorris T.C. & Anchel M. J Am Chem Soc 1963, 85, 831.
- Structure-activity relationships of illudins: analogs with improved therapeutic index. McMorris T.C. et al. J. Org. Chem. 1992, 57, 6876.