Hydroxyectoine

Hydroxyectoine

$56.00 - 25 mg

$196.00 - 100 mg

All prices in Australian dollars

Code
BIA-H2231
Synonyms
(S,S)-β-Hydroxyectoine, 5-Hydroxyectoine, Hydroxyectoin, Pyrostatin A, Pyrostatine A, β-Hydroxyectoine, (4S,5S)-1,4,5,6-Tetrahydro-5-hydroxy-2-methyl-4-pyrimidinecarboxylic acid
CAS #
165542-15-4
Molecular Formula
C6H10N2O3
Molecular Weight
158.16
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

Download Data Sheets

Product Data Sheet

Application Notes

Hydroxyectoine (pyrostatin A) is an uncommon 2-iminopyrrolidine produced halophilic and thermophilic bacteria and some Archaea. Hydroxyectoine is osmo- and cytoprotective and is a chemical chaperone, stabilising protein functionality. Hydroxyectoine has anti-inflammatory properties.

References

  • Isolation and synthesis of (−)-(5S)-2-imino-1-methylpyrrolidine-5- carboxylic acid from Cliona tenuis: Structure revision of pyrostatins. Castellanos L. et al. Organic Lett. 2006, 8, 4967.
  • Determination of the ectoine and hydroxyectoine in moderately halophilic bacteria by hydrophilic interaction chromatography. He B. et al. Fenxi Shiyanshi 2016, 35, 93.
  • Ectoines as novel anti-inflammatory and tissue protective lead compounds with special focus on inflammatory bowel disease and lung inflammation. Bethlehem L. & van Echten-Deckert G. Pharmacol Res. 2021, 164, 105389.
  • Hydroxyectoine protects Mn-​depleted photosystem II against photoinhibition acting as a source of electrons. Yankvin D.V. et al. Photosynthesis 2019, 141, 165.

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