Heveadride is a nonadride lactone related to byssochlamic acid, produced by several fungal species, including Helminthosporium heveae and Bipolaris heveae. Heveadride is active against various filamentous fungi and some human pathogenic yeasts such as Trichosporon sp.. Heaveadride induces dose-dependent down-regulation of TNFα-induced NF-κB activity in human chronic myeloid leukemia cells with IC50s of 82 ± 11 μM. Heveadride has not been extensively studied.
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