Hesperidin methyl chalcone

Hesperidin methyl chalcone

$60.00 - 1 mg

$210.00 - 5 mg

All prices in Australian dollars

Code
BIA-H3069
Synonyms
Hesperidin methylchalcone, Hesperitin methylchalkon
CAS #
24292-52-2
Molecular Formula
C29H36O15
Molecular Weight
624.6
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol and DMSO.

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Application Notes

Hesperidin methyl chalcone is a ring opened flavanone glycoside, found in large quantities in many citrus fruits such as lemons, limes and oranges. Hesperidin methyl chalcone has antiquorum sensing activity, as well as antiinflammatory and antioxidant activity. Hesperidin methyl chalcone reduces TNF-α-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to the inhibition of adhesion of monocytes to endothelium.

References

  • Prithiviraj S.R. et al. (2023). Hesperidin methyl chalcone, a citrus flavonoid, inhibits Aeromonas hydrophila infection mediated by quorum sensing. Microb. Pathog., 177, 106029.
  • Nizamutdinova I.T. et al. (2008). Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells. Int. Immunopharmacol., 8, 670.

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