Hancockinone A

Hancockinone A

Hancockinone A

$265.00 - 0.5 mg

$930.00 - 2.5 mg

All prices in Australian dollars

Code
BIA-H3136
Synonyms
-
CAS #
-
Molecular Formula
C24H22O7
Molecular Weight
422.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Hancockinone A is a novel polycyclic metabolite produced by A. hancockii following CRISPR-based pathway activation. Hancockinone A features an unprecedented prenylated 6/6/6/5 tetracarbocyclic skeleton. Hancockinone A displays moderate in vitro antibacterial activity against Bacillus subtilis and Staphylococcus aureus and no significant antitumor activity.

References

  • Genome mining of Aspergillus hancockii unearths cryptic polyketide hancockinone A featuring a prenylated 6/6/6/5 carbocyclic skeleton. Li t. et al. Org. Lett. 2021, 23, 8789.

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