Geministatin C

Geministatin C

Geministatin C

$190.00 - 0.1 mg

$665.00 - 0.5 mg

All prices in Australian dollars

Code
BIA-G3199
Synonyms
-
CAS #
-
Molecular Formula
C31H48O9
Molecular Weight
564.7
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Geministatin C is a minor co-metabolite and degradation product of geministatin A, a recently described depside antibiotic isolated from the fungus Austroacremonium gemini. Geministatin C is formed by acid hydrolysis in methanol to cleave the depside ester of geministatin A. Geministatin C possesses weak cytotoxic activity, but was inactive against S. aureus, MRSA and S. cerevesiae.

References

  • Geministatins: new depside antibiotics from the fungus Austroacremonium gemini. Crombie A. et al. J. Antibiot. 2024, 77, 639.
  • The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains. Sbaraini N. et al. Chem. Sci. 2024, 15,18872.

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