Fusidate sodium
Fusidate sodium
$195.00 - 25 mg
$55.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-F1259
- Synonyms
- Ramycin, NSC 56192, SQ 16603, SQ 16603
- CAS #
- 751-94-0
- Molecular Formula
- C31H47NaO6
- Molecular Weight
- 538.7
- Purity
- >98% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
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Application Notes
Sodium fusidate is the more water soluble sodium salt of fusidic acid, a steroidal metabolite of Fusidum coccineum which is a potent Gram positive antibiotic. Fusidic acid inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Fusidic acid also suppresses NO lysis of pancreatic islet cells.
References
- Fusidic acid: a new antibiotic. Godtfredson W. O. et al., Nature 1962, 193, 987.
- On the mode of action of fusidic acid. Harvey C. L. et al., Biochemistry 1969, 5, 3320.
- Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics. Tanaka N. et al., BBRC 1968, 30, 278.