Fusidate sodium

Fusidate sodium

$100.00 - 25 mg

$350.00 - 100 mg

All prices in Australian dollars

Code
BIA-F1259
Synonyms
Ramycin, NSC 56192, SQ 16603, SQ 16603
CAS #
751-94-0
Molecular Formula
C31H47NaO6
Molecular Weight
538.7
Purity
>98% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Sodium fusidate is the more water soluble sodium salt of fusidic acid, a steroidal metabolite of Fusidum coccineum which is a potent Gram positive antibiotic. Fusidic acid inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Fusidic acid also suppresses NO lysis of pancreatic islet cells.

References

  • Fusidic acid: a new antibiotic. Godtfredson W. O. et al., Nature 1962, 193, 987.
  • On the mode of action of fusidic acid. Harvey C. L. et al., Biochemistry 1969, 5, 3320.
  • Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics. Tanaka N. et al., BBRC 1968, 30, 278.

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