Frequentin

Frequentin

$190.00 - 0.50 mg

$665.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-F1702
CAS #
29119-03-7
Molecular Formula
C14H20O4
Molecular Weight
252.31
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Frequentin is a polar neutral metabolite isolated from P. frequentans by Curtis and co-workers at ICI in 1951. Frequentin is a cyclitol-like metabolite bearing a heptadiene chain. Frequentin, the aldehyde analogue of palitantin, exists as the hydroxymethylene in solution. Frequentin has been found in a number of Penicillium species and is a useful metabolite for chemotaxonomy of the genus. Frequentin is a potent antifungal active with minimal toxicity to mammalian cells.

References

  • Frequentin: an antibiotic produced by some strains of Penicillium frequentans Westling. Curtis P.J. et al., Nature 1951, 167, 557.
  • A structural relationship between frequentin and palitantin. Curtis P.J. and Duncanson L.A., Biochem. J. 1952, 51, 276.

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