$290.00 - 1 mg
$1,015.00 - 5 mg
All prices in Australian dollars
- Clostomicin B1, Lipiarmycin A3, Tiacumicin B, OPT 80
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Fidaxomicin is a recently marketed antibiotic with a confusing history dating back to its original isolation in 1975. Fidaxomicin is the major analogue of a family of macrocyclic lactones, isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora.
- Lipiarmycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies. Parenti F. et al., J. Antibiot. 1975, 28, 247.
- Clostomicins, new antibiotics produced by Micromonospora echinospora subsp. armeniaca subsp. nov. I. Production. Omura S. et al., J. Antibiot. 1986, 39, 1407.
- Tiacumicins, a novel complex of 18-membered macrolide antibiotics. I. Taxonomy, fermentation and antibacterial activity. Theriault R.J. et al., J. Antibiot. 1987, 40, 567.