Euphol acetate
Application Notes
Euphol acetate is a triterpene isolated from the latex of Euphorbia broteri and other members of the genus. Little is published on its biological activity, however, euphol itself is reported to have anti-inflammatory activity and inhibits tumor promotion.
References
- Triterpenes from Euphorbia broteri. De Pascual T. et al., Phytochem. 1987, 26, 1767.
- The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice. Passos G.F. et al., Eur. J. Pharmacol. 2013, 698, 413.
- Inhibitory effect of euphol, a triterpene alcohol from the roots of Euphorbia kansui, on tumour promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Yasukawa K. et al., J. Pharm. Pharmacol. 2000, 52, 119.