Erythromycin B

Erythromycin B

$150.00 - 1 mg

$525.00 - 5 mg

All prices in Australian dollars

Code
BIA-E1350
Synonyms
12-Deoxyerythromycin, Berythromycin
CAS #
527-75-3
Molecular Formula
C37H67NO12
Molecular Weight
717.9
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Erythromycin B (12-deoxyerythromycin A) is a minor co-metabolite of erythromycin produced Saccharopolyspora erythreae. Erythromycin B exhibits broad spectrum antibiotic activity, albeit less potent than erythromycin A. Erythromycin B played an integral part of the SAR studies of semi-synthetic erythromycins, however none reached clinical development.

References

  • HPLC as a rapid means of monitoring erythromycin and tetracycline fermentation processes. Tsuii K. & Goetz J.F. J. Antibiot. 1978, 31, 302.
  • Antibacterial activities of erythromycins A, B, C, and D and some of their derivatives. Kibwage O. et al., Antimicrob. Agents Chemother. 1985, 28, 630.

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