Enniatin A1
Enniatin A1
$205.00 - 1 mg
$718.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-E1166
- Synonyms
- 2-(N-Methyl-L-valine)enniatin A
- CAS #
- 4530-21-6
- Molecular Formula
- C35H61N3O9
- Molecular Weight
- 667.9
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes
Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex .
References
- Ionophore antibiotics produced by the fungus Fusarium orthoceras var. enniatum and other Fusaria. Gaumann E. et al., Experientia 1947, 3, 202.
- "Sandwich" complexation in cyclopeptides and its implications in membrane processes. Ivanov V.T. Ann. N. Y. Acad. Sci. 1975, 264, 221.
- Interaction of cyclic peptides and depsipeptides with calmodulin. Mereish K.A. et al., Pept. Res. 1990, 3, 233.
- Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells. Dornetshuber R. et al., Chem. Res. Toxicol. 2007, 20, 465.