Drimendiol

Drimendiol

$230.00 - 1 mg

$805.00 - 5 mg

All prices in Australian dollars

Code
BIA-D1771
Synonyms
(-)-11,12-Dihydroxydrimene, (-)-Drimenediol, 11,12-Drihydroxydrimene, Polygodiol
CAS #
34437-62-2
Molecular Formula
C15H26O2
Molecular Weight
238.37
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Drimendiol is the sesquiterpene dialcohol of polygodial, found in a number of plant species native to Australia and New Zealand. More recently, drimendiol was prepared from polygodial isolated from Tasmannia lanceolata by Smith and colleagues at the University of Tasmania, Australia. Drimendiol's bioactivity has received little attention but it is reported as a quorum sensing inhibitor.

References

  • Practical isolation of polygodial from Tasmannia lanceolata: a viable scaffold for synthesis. Just J. et al. Org. Biomol. Chem., 2015, 13, 11200
  • Drimendiol, a drimane sesquiterpene with quorum sensing inhibition activity. Paza C. et al., Nat. Prod. Commun. 2013, 8, 147.
  • Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes. Hemquet M.G.L. et al., Plant J. 2017, 90, 1052.

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