Demethoxyviridiol
Demethoxyviridiol
$285.00 - 1 mg
$1,000.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-D1025
- CAS #
- 56617-66-4
- Molecular Formula
- C19H16O5
- Molecular Weight
- 324.3
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. NOTE: stability problems if stored in methanol for protracted periods.
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Application Notes
Demethoxyviridiol is a fungal metabolite belonging to the wortmannin and viridin classes. An inhibitor of phosphatidylinositol 3-kinase, demethoxyviridiol affects phospholipid signalling and proliferation of Swiss 3T3 cells.
References
- Inhibition of phospholipid signalling and proliferation of Swiss 3T3 cells by the wortmannin analogue demethoxyviridin. Cross M.J. et al., Biochim Biophys Acta. 1997, 1362, 29.
- Effects of phosphatidylinositol-3-kinase inhibitors on degranulation and gene induction in allergically triggered mouse mast cells. Pendl G.G. et al., Int Arch Allergy Immunol. 1997, 112, 392.
- Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors. Petritsch C. et al., Eur J Biochem. 1995, 230, 431.