$138.00 - 1 mg
$483.00 - 5 mg
All prices in Australian dollars
- Zygosporin A
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumor agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology.
- Antitumor activity of cytochalasin D: Katagiri K. and Matsuura S. J. Antibiot. 1971, 24, 722.
- Effects of cytochalasin and phalloidin on actin: Cooper J. A. J. Cell. Biol. 1987, 105, 1473
- Myosin-actin interaction plays an important role in human immunodeficiency virus type 1 release from host cells. H. Sasaki, H. et al., ; PNAS 1995, 92, 2026.