Cordycepin
Cordycepin
$70.00 - 1 mg
$245.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-C1688
- Synonyms
- 3'-Deoxyadenosine; 9-Cordyceposidoadenosine; Adenine coryceposide; Cordycepine; NSC 401022; NSC 63984
- CAS #
- 73-03-0
- Molecular Formula
- C10H13N5O3
- Molecular Weight
- 251.24
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO.
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Application Notes
Cordycepin is a nucleoside metabolite first isolated by Cunningham in 1951 as an antibacterial from Cordyceps militaris, an ascomycete that parasitises soil dwelling caterpillars. Cordycepin was subsequently proven to be a simple analogue of adenosine, 3’-deoxyadenosine. Cordycepin is a potent antitumor active. Its production, chemistry, biosynthesis and bioactivity were reviewed by Suhadolink in 1970. More recently, natural medicinal preparations of C. militaris have found wide appeal and sparked re-investigation into cordycepin’s effects on abnormal gut dwelling bacteria.
References
- Cordycepin, a metabolic product from cultures of Cordyceps militaris (Linn.) Link. Part I. Isolation and characterisation. Cunningham K.G. et al., J. Chem. Soc. 1951, 2299.
- Cordycepin, a metabolic product from cultures of Cordyceps militaris (Linn.) Link. Part II. The structure of cordycepin. Bentley H.R. et al., J. Chem. Soc. 1951, 2301.
- An improved method of isolation and determination of cordycepin. Kredich N.M. and Guarino A.J., Biochim. Biophys. Acta 1960, 41, 363.
- Cordycepin: selective growth inhibitor derived from liquid culture of Cordyceps militaris against Clostridium spp. Ahn Y-J. et al., J. Agric. Food Chem. 2000, 48, 2744.