Cordycepin

Cordycepin

$70.00 - 1 mg

$245.00 - 5 mg

All prices in Australian dollars

Code
BIA-C1688
Synonyms
3'-Deoxyadenosine; 9-Cordyceposidoadenosine; Adenine coryceposide; Cordycepine; NSC 401022; NSC 63984
CAS #
73-03-0
Molecular Formula
C10H13N5O3
Molecular Weight
251.24
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Product Data Sheet

Application Notes

Cordycepin is a nucleoside metabolite first isolated by Cunningham in 1951 as an antibacterial from Cordyceps militaris, an ascomycete that parasitises soil dwelling caterpillars. Cordycepin was subsequently proven to be a simple analogue of adenosine, 3’-deoxyadenosine. Cordycepin is a potent antitumor active. Its production, chemistry, biosynthesis and bioactivity were reviewed by Suhadolink in 1970. More recently, natural medicinal preparations of C. militaris have found wide appeal and sparked re-investigation into cordycepin’s effects on abnormal gut dwelling bacteria.

References

  • Cordycepin, a metabolic product from cultures of Cordyceps militaris (Linn.) Link. Part I. Isolation and characterisation. Cunningham K.G. et al., J. Chem. Soc. 1951, 2299.
  • Cordycepin, a metabolic product from cultures of Cordyceps militaris (Linn.) Link. Part II. The structure of cordycepin. Bentley H.R. et al., J. Chem. Soc. 1951, 2301.
  • An improved method of isolation and determination of cordycepin. Kredich N.M. and Guarino A.J., Biochim. Biophys. Acta 1960, 41, 363.
  • Cordycepin: selective growth inhibitor derived from liquid culture of Cordyceps militaris against Clostridium spp. Ahn Y-J. et al., J. Agric. Food Chem. 2000, 48, 2744.

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