Coprogen is a dark red metabolite originally isolated from Pilobolus species in 1952 by researchers from American Cyanamid. Coprogen is a rare amphiphilic siderophore that acts as a growth factor for coprophilic fungi. Secreted coprogen can be scavenged by some Gram-negative bacteria via the TonB-dependent transporter FhuE. Coprogen has weak phytotoxic activity in a leaf-wounding assay.
- Coprogen, a new growth factor for coprophilous fungi. Hesseltine C.W. et al. J Am Chem Soc. 1952, 74, 1362.
- Determination of the molecular basis for coprogen import by Gram-negative bacteria. Grinter R. & Lithgow T. IUCrJ 2019, 6, 401-411.
- Production of two phytotoxic metabolites by the fungus Alternaria cassia. Ohra J. et al. Biosci Biotech Biochem. 1995, 59, 1782.