Cladobotric acid E

Cladobotric acid E

Cladobotric acid E

$315.00 - 1 mg

$1,105.00 - 5 mg

All prices in Australian dollars

Code
BIA-C3184
Synonyms
-
CAS #
876152-18-0
Molecular Formula
C27H36O6
Molecular Weight
456.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

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Product Data Sheet

Application Notes

Cladobotric acid E is an analogue of a family of related tetradehydrodecalin trienoic acid polyketides isolated from an undescribed Cladobotryum strain by Munro, Blunt and co-workers at Canterbury University, New Zealand in 2006. Cladobotric acid E exhibits notable activity against a murine P388 leukemia cell line and is moderately active against methicillin-resistant and vancomycin intermediate S. aureus. Cladobotric acid E exhibits strong antifungal activity against Aspergillus fumigatus and Candida auris strains.

References

  • Cladobotric acids A−F:  New cytotoxic polyketides from a New Zealand Cladobotryum sp. Mitova M.I. et al. J. Org. Chem. 2006, 71, 492.
  • Cladobotric acids: Metabolites from cultures of Cladobotryum sp., semisynthetic analogues and antibacterial activity. Dao T-T. et al. J. Nat. Prod. 2022, 85, 572.
  • Hakuhybotrol, a polyketide produced by Hypomyces pseudocorticiicola, characterized with the assistance of 3D ED/MicroED. Watanabe Y. et al. Org. Biomol. Chem. 2023, 21, 2320.

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