Circumdatin A
Application Notes
Circumdatin A, produced by Aspergillus sp., was first reported in 1999 by Rahbaek and colleagues, University of Copenhagen, Denmark. The structure of circumdatin A was revised as a unique oxepine in 2008 using X-ray crystallography. Lack of availability has prevented investigation of its biological activity to date.
References
- Circumdatin A, B, and C: Three new benzodiazepine alkaloids isolated from a culture of the fungus Aspergillus ochraceus. Rahbaek L. et al. J Org Chem. 1999, 64, 1689.
- Structure revision of circumdatins A and B, benzodiazepine alkaloids produced by marine fungus Aspergillus ostianus, by X-ray crystallography. Ookura R. et al. J Org Chem. 2008, 73, 4245.