Chrodrimanin B

Chrodrimanin B

$215.00 - 0.50 mg

$755.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-C1968
CAS #
132196-54-4
Molecular Formula
C27H32O8
Molecular Weight
484.54
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Application Notes

Chrodrimanin B is a meroterpenoid isolated from Penicillium sp. with insecticidal properties. Chrodrimanin B attenuates the effect of GABA. Chrodrimanin B blocks the GABA​-​induced current in insect models, when delivered at 1 μM for 1 min prior to co-​application with transmitter GABA.  

References

  • Novel chrodrimanin compounds and their manufacture with Penicillium. Matuso N. et al. Jpn. Kokai Tokkyo Koho (1990), JP 02221277 A 19900904.
  • Elucidation and heterologous reconstitution of chrodrimanin B biosynthesis. Bai T. et al. Org Lett 2018, 20, 7504.
  • Meroterpenoid Chrodrimanins Are Selective and Potent Blockers of Insect GABA-​Gated Chloride Channels. Xu Y. et al. PloS One 2015, 10, e0122629.

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