Chloramphenicol acetate
Chloramphenicol acetate
$180.00 - 5 mg
$630.00 - 25 mg
All prices in Australian dollars
- Code
- BIA-C1476
- Synonyms
- 3-O-Acetylchloramphenicol, Chloramphenicol 3-acetate
- CAS #
- 10318-16-8
- Molecular Formula
- C13H14Cl2N2O6
- Molecular Weight
- 365.2
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes
Chloramphenicol acetate is a naturally-occurring co-metabolite of chloramphenicol in Streptomyces venezuelae with albeit significantly lower potency. Chloramphenicol acetate is the major product of chloramphenicol acetyltransferase, the major resistance mechanism to chloramphenicol.
References
- Isolation of 3′-O-acetylchloramphenicol: A possible intermediate in chloramphenicol biosynthesis. Gross F. et al., Bioorg. Med. Chem. Letters 2002, 12, 283.
- Chloramphenicol acetyltransferase Shaw W.V. & Leslie A.G.W. Ann. Rev. Biophys. Biophys. Chem. 1991, 20, 363.