Capricostatin A

Capricostatin A

Capricostatin A

$255.00 - 0.5 mg

$895.00 - 2.5 mg

All prices in Australian dollars

Code
BIA-C3210
Synonyms
-
CAS #
-
Molecular Formula
C36H50O12
Molecular Weight
674.8
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Capricostatin A is a major analogue of a parallel series of analogues of geministatin A, a recently described depside antibiotic isolated from the fungus Austroacremonium gemini. Capricostatin A contains a Δ15,16 double bond in the C15 side-chain and is the Δ18,19 dihydro analogue of geministatin A. Capricostatin A exhibits potent antibacterial activity and no cytotoxic activity.

References

  • Geministatins: new depside antibiotics from the fungus Austroacremonium gemini. Crombie A. et al. J. Antibiot. 2024, 77, 639.
  • The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains. Sbaraini N. et al. Chem. Sci. 2024, 15, 18872.

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