Calcimycin

Calcimycin

$90.00 - 1 mg

$315.00 - 5 mg

All prices in Australian dollars

Code
BIA-C1236
Synonyms
A 23187, Calimycin
CAS #
52665-69-7
Molecular Formula
C29H37N3O6
Molecular Weight
523.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Product Data Sheet

Application Notes

Calcimycin is a potent calcium ionophore isolated from Streptomyces chartreusis in 1974. Calcimycin is a spiroketal substituted by pyrollic and benzoxazolyl groups which afford its high affinity and selectivity for calcium. Calcimycin exhibits broad biological activity against bacteria, fungi and protozoa. It has found wide application as a research tool for calcium-regulated cellular events.

References

  • Structure of A23187, a divalent cation ionophore. Chaney M. O. et al., JACS 1974, 96, 1932.
  • A23187: a divalent cation ionophore. Reed P. W. & Lardy H. A. J. Biol. Chem. 1972, 247, 6970.
  • Biological applications of ionophores. Pressman B. C. et al., Ann. Rev. Biochem. 1976, 45, 501.

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