Calcimycin
Calcimycin
$95.00 - 1 mg
$335.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-C1236
- Synonyms
- A 23187, Calimycin
- CAS #
- 52665-69-7
- Molecular Formula
- C29H37N3O6
- Molecular Weight
- 523.6
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in methanol, DMSO. Poor water solubility.
Download Data Sheets
Application Notes
Calcimycin is a potent calcium ionophore isolated from Streptomyces chartreusis in 1974. Calcimycin is a spiroketal substituted by pyrollic and benzoxazolyl groups which afford its high affinity and selectivity for calcium. Calcimycin exhibits broad biological activity against bacteria, fungi and protozoa. It has found wide application as a research tool for calcium-regulated cellular events.
References
- Structure of A23187, a divalent cation ionophore. Chaney M. O. et al., JACS 1974, 96, 1932.
- A23187: a divalent cation ionophore. Reed P. W. & Lardy H. A. J. Biol. Chem. 1972, 247, 6970.
- Biological applications of ionophores. Pressman B. C. et al., Ann. Rev. Biochem. 1976, 45, 501.
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