Berkeleylactone L
Application Notes
Berkeleylactone L was first reported from reinvestigation of the fungus Penicillium turbatum in 2021 by Stierle and colleagues, University of Montana, USA after an initial 1977 study revealed the compound A26771B which shares structural similarities to the previous berkeleylactones. The berkeleylactones are a family of macrolide antibiotics, with berkeleylactone L consisting of a 16-membered ring with one hydroxyl group appended. Berkeleylactone L showed weaker antimicrobial activity than other congeners isolated.
References
- Stierle A.J. et al. (2021). Berkeleylactones and a citreohybriddione analogue from Penicillium turbatum. J. Nat. Prod., 84, 3064
- Stierle A.J. et al. (2008). The berkeleyamides, amides from the acid lake fungus Penicillum rubrum. J. Nat. Prod., 71, 856.
- Stierle A.J. et al. (2014). Bioactive secondary metabolites from acid mine waste extremophiles. Nat. Prod. Commun., 9, 1037.